Zvese zvekuomesa chando, lyophilizer uye muchina wekuomesa nechando zvinopedza kupera mvura mumuviri kuburikidza nekuomesa nechando-tekinoroji yekuomesa neiyo lyophilization, uye maitiro ese akakamurwa kuita matanho matatu akakosha: pre-kuomesa nechando, yekutanga kuomesa (sublimation), uye yechipiri drying (desorption), iyo inoshanda kune ese ari maviri bench{2}top philize dryer.
Danho rekutanga ndere-kutonhora. Vacuum freeze dryer inokurumidza kuderedza tembiricha yemukati kusvika pazasi pepoindi katatu yemvura, ichiomesa hunyoro hwese muchinhu kuita aizi yakasimba. Danho iri ndiro hwaro hwelyophilization, uhwo hunogona kudzivirira kuti zvinhu zvisanyunguduke uye kukuvadzwa kwechimiro panguva inotevera-kuomeswa, uye kudzivirira zvinhu zvinobatika pakupisa{4}}zvisinganzwisisike.
Nhanho yechipiri ndeyekutanga kuomesa, inozivikanwawo se sublimation drying. Muchina wekuomesa nechando unotanga vacuum system kuita yakaderera-pressure vacuum environment mukati mechamber. Pasi petembiricha yakaderera uye mamiriro ekutsvaira, aizi yakasimba muchinhu ichi inonyungudika mumhute yemvura isinganyungudike mumvura ine mvura, inobvisa zvinopfuura 80% yehunyoro hwezvinhu.
Danho rechitatu kuomeswa kwechipiri, kureva desorption drying. Industrial freeze dryer uye bhenji-top freeze dryer zvinosimudza tembiricha zvakakodzera uye kugadzirisa vacuum℃kuti ibvise mvura yakasungwa yasara mumidziyo. Danho iri rinodzikisirazve hunyoro hwechigadzirwa chapera uye rinoita kuti{3}}kuchengetedzeka kwenguva refu kwechando{4}}zvigadzirwa zvakaomeswa.
Iko kurongeka chaiko kwematanho matatu kunogadzirisa mhando yekupedzisira yeiyo lyophilization zvigadzirwa. -muchina wekuomesa chando wemhando yepamusoro uye michina ye lyophilizer inokwanisa kugadziridza tembiricha, vacuum℃uye nguva dzinoenderana nemhando dzakasiyana, kudzivirira kupera kwechigadzirwa, oxidation uye kurasikirwa kwechinhu chinokonzerwa nechando chisina kufanira-kuoma.
Ingave iri murabhoritari diki-kugadziridza mabhechi kana kugadzirwa kwakawanda muindasitiri, kuomesa chando-kuomesa uye kudzora maitiro e lyophilization ndiyo kiyi yekugadzira yakakwirira-yakaomeswa yemhando yepamusoro-yakaomeswa neyakaomeswa, inovawo kukosha kwehunyanzvi hwekugadzira vacuum freeze dryer uye kuomesa michina yemichina yekuomesa.
